Europa Peptides
Retatrutide vs tirzepatide vs semaglutide
These three peptides belong to the incretin analogues, but they differ in the number of receptors they target in research. Below is a neutral, scientific comparison.
Comparison table
| Property | Retatrutide | Tirzepatide | Semaglutide |
|---|---|---|---|
| Receptors | GLP-1, GIP and glucagon (triple agonist) | GLP-1 and GIP (dual agonist) | GLP-1 (mono agonist) |
| Research code | LY3437943 | LY3298176 | NN9535 |
| Status | In clinical research (phase 3) | Approved medicine (prescription) | Approved medicine (prescription) |
| Available at Europa Peptides | Yes, 10 mg and 20 mg (RUO) | No | No |
What makes retatrutide different?
Retatrutide is the first peptide in this series that, in research, acts on three receptors at once: GLP-1, GIP and glucagon. That is why it is called a triple agonist. It is currently being studied in large clinical trials and is not an approved medicine.
Tirzepatide and semaglutide
Tirzepatide combines GLP-1 and GIP activity, semaglutide acts only on the GLP-1 receptor. Both are approved medicines available only on prescription through a pharmacy. Europa Peptides does not sell them.
Ordering retatrutide for research
We offer retatrutide as a 10 mg vial or as a 20 mg bundle (2x 10 mg, incl. 6 ml bacteriostatic water). Every batch is HPLC-tested at 99%+ purity.
Order directly
Frequently asked questions
Is retatrutide the same as tirzepatide?
No. Tirzepatide targets two receptors (GLP-1 and GIP), retatrutide three (GLP-1, GIP and glucagon).
Do you sell semaglutide or tirzepatide?
No, those are approved prescription medicines. We only supply research peptides for laboratory research.
Which retatrutide sizes are available?
10 mg per vial, or 20 mg as a bundle (2x 10 mg) with 6 ml bacteriostatic water.
All Europa Peptides products are intended for laboratory research only (Research Use Only). Not for human or veterinary use.