Europa Peptides
BPC-157 vs TB-500: the differences explained
BPC-157 and TB-500 are often mentioned together in preclinical research, but they are very different peptides. Below we compare origin, structure, research areas and practical matters such as reconstitution and storage.
Comparison at a glance
| Property | BPC-157 | TB-500 |
|---|---|---|
| Origin | Synthetic fragment derived from a gastric juice protein | Synthetic fragment of thymosin beta-4 |
| Length | 15 amino acids | Short active fragment (incl. LKKTETQ motif) |
| Molecular weight | approx. 1419 g/mol | depends on fragment (approx. 889 g/mol for Ac-LKKTETQ) |
| Research areas (preclinical) | Tissue models, angiogenesis, gastrointestinal models | Cell migration, actin dynamics, tissue models |
| Supplied as | Lyophilized powder in vial | Lyophilized powder in vial |
| Storage | Dry: cool and dark; after reconstitution 2–8 °C | Dry: cool and dark; after reconstitution 2–8 °C |
What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide. In the literature it is mainly studied in animal and cell models around tissue repair, blood vessel formation and the gastrointestinal tract. No human clinical use is approved.
What is TB-500?
TB-500 is a synthetic fragment of thymosin beta-4, a protein involved in regulating actin within cells. Researchers use it in models of cell migration and tissue organisation.
Why are they studied together?
Because both peptides appear in preclinical tissue models but are studied through different mechanisms, some studies compare them side by side. That is why they are often mentioned as a pair. Europa Peptides supplies both as separate vials so researchers can design their own setup.
Reconstitution and calculation
Both peptides are supplied lyophilized and come with 3 ml of bacteriostatic water as standard. Our free peptide calculator quickly works out concentrations per ml and per unit.
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Frequently asked questions
What is the main difference between BPC-157 and TB-500?
Origin and mechanism: BPC-157 is derived from a gastric protein, TB-500 from thymosin beta-4. They are studied in different preclinical models.
Are BPC-157 and TB-500 tested?
All batches are HPLC-tested at 99%+ purity. Available analyses are on our lab results page.
How fast do you ship?
Orders placed before 16:00 (Mon-Sat) ship the same day, from the Netherlands to the whole EU.
All Europa Peptides products are intended for laboratory research only (Research Use Only). Not for human or veterinary use.